COVID-19 pandemic: the existing challenges and available solution;evidence from a systematic review

Coronavirus disease (COVID-19) is presently the most important topic worldwide. However, no vaccine or specific anti-viral treatment for the disease has been shown to be effective. In this emergency identifying risk factors preventive measures and estimating challenges which control available drug options for COVID-19 are key to mitigating the severity of the pandemic until specific drugs or vaccines become available. Therefore, this study aims to identify possible factors which affect these drug options. This study searched PubMed database using necessary Boolean operators from December 31st to March 31st, 2020 in order to identify common risk factors preventive measures information regarding control challenges & evidence on the available drug options against COVID-19. Risk factors were found to be human-animal interactions males aged people and people with co-morbidity. Furthermore, protective factors comprised of personal hygiene etiquette maintenance rapid identification isolation and informing (3I tools) of the COVID-19 cases and media coverage on COVID-19. Till date anti-viral drugs like Remdesivir chloroquine lopinavir/ritonavir and traditional Chinese medicine (TCM) are available options to fight against COVID-19. More research is needed to determine other how to control the disease until specific treatment options are available as well as risk factors and preventive measures.

Is COVID-19 spreading and curing silently: an observation of three family clusters in Bangladesh.

Objectives The number of coronavirus disease (COVID-19) cases is increasing in Bangladesh. Many people have suffered from symptoms like COVID-19 during this pandemic, and some people have cured without taking any treatment or taking minor pharmacological and non-pharmacological treatments. However, they might be spreading their infections among their family members and perhaps in the community. It is unsure that individuals with COVID-19-like symptoms are positive with COVID-19, but our concern is, during this pandemic, any types of symptoms such as flu-like symptoms should have been taken seriously. This study was observed in the cases from three families with COVID-19 like symptoms. Case presentation This observational study was done between May 20 and Jun 2, 2020, in Bangladesh. The members of the inspected families shared COVID-19 like symptoms that were lasted for 3-10 days. Conclusions COVID-19 might be spread and cured silently in Bangladesh, which recommends that awareness is needed throughout the country to prevent the spreading of the disease.